منابع مشابه
Interleukin Antagonists
There is strong experimental and clinical support for a causal role of immune dysregulation and inflammation in atherosclerosis and heart failure. Atherosclerotic lesions are infiltrated by monocytes, macrophages, and T lymphocytes (predominantly Th1). Cytokines, including interleukin-6 (IL6) and tumor necrosis factor-α (TNF-α), are released by the infiltrating inflammatory cells and stimulate ...
متن کاملInterleukin-1 antagonists in Mevalonate Kinase Deficiency
Background Mevalonate Kinase Deficiency (MKD) is one of the autoinflammatory fever syndromes, caused by mutations in the MKD gene. Systemic inflammatory symptoms may be mild to severe leading to early death, and recurrent bacterial infections frequently develop in the disease course. On demand NSAID and steroids are the most commonly used. Few case-reports suggested that interleukin-1 (IL-1) an...
متن کاملInterleukin 2 receptor antagonists for kidney transplant recipients.
BACKGROUND Interleukin 2 receptor antagonists (IL2Ra) are used as induction therapy for prophylaxis against acute rejection in kidney transplant recipients. Use of IL2Ra has increased steadily, with 38% of new kidney transplant recipients in the United States, and 23% in Australasia receiving IL2Ra in 2002. OBJECTIVES This study aims to systematically identify and summarise the effects of usi...
متن کاملInterleukin-6 antagonists for the management of hypertension.
Interleukin-6 Antagonists for the Management of Hypertension To the Editor: I read with great interest the recent article published by Luther et al1 in the December 2006 issue of Hypertension, which focused on how angiotensin II induces interleukin (IL)-6 in humans. The authors suggest that angiotensin II performs this function through a mineralocorticoid receptor–dependent mechanism. I would l...
متن کاملInterleukin-10 and interleukin-1 receptor antagonists increase during cardiac surgery.
BACKGROUND It has been reported that inflammatory cytokines such as interleukin-8 and 6 (IL-8, IL-6) increase during cardiac surgery and caused postoperative cardiac dysfunction. Therefore, it is important to investigate changes of suppressive cytokines such as IL-10, interleukin-4 (IL-4) and interleukin-1 receptor antagonist (IL-1ra) during cardiac surgery. METHOD Serum levels of cytokines a...
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ژورنال
عنوان ژورنال: Circulation: Cardiovascular Imaging
سال: 2017
ISSN: 1941-9651,1942-0080
DOI: 10.1161/circimaging.117.006919